●ResPRE ●DeepMSA Hi All, and Privacy ●HPSF How to interpret protein function after mutation? Can anybody tell me? DAVID now provides a comprehensive set of functional annotation tools for investigators to understand biological meaning behind large list of genes. What In Your Opinion Is The Best Tool For Protein Function Prediction? ●ThreaDom GeneCards ®: The Human Gene Database. ●MetaGO ●CASP9 We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool. Examples: Q8MMJ7, Q9UBU3 The same holds true for isoform-specific functions. ●MR-REX SIB - Swiss Institute of Bioinformatics; CPR - Novo Nordisk Foundation Center Protein Research; EMBL - European Molecular Biology Laboratory ocurence frequency of all ligands in BioLiP, ligand binding affinity (from the original literature, plus. Online resources and software to analyze protein function. Orthologous proteins in different species most often share function, but paralogy (that is, divergence following duplication of the original gene) does not guarantee common function. ●I-TASSER-MR ●SVMSEQ How to study about a novel protein and its function, if there is no database or antibody is available to study the ... biology in order to predict and analyze a new unknown protein function. ●DECOYS InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. ●ModRefiner The recent progress in genome sequencing has led to a rapid enrichment of protein databases with an unprecedented variety of deduced protein sequences, most of them without a documented functional role. ●3DRobot Customized protein production request can be made for any protein in this database by clicking on the corresponding button under "Quick Quote". Agreement ●ATPbind It is an undirected graph. There are no wrong answers rather opinions that I would value. Phylogeny-based Protein Function Prediction SIFTER (S tatistical I nference of F unction T hrough E volutionary R elationships) is a statistical approach to predicting protein function that uses a protein family's phylogenetic tree, as the natural structure for representing protein relationships. ●REMO ●POTENTIAL The Protein database is a collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. The COMBREX database (COMBREX-DB; combrex.bu.edu) is an online repository of information related to (i) experimentally determined protein function, (ii) predicted protein function, (iii) relationships among proteins of unknown function and various types of experimental data, including molecular function, protein structure, and associated phenotypes. Can you define what you mean with "newly discovered protein" ? BioGRID is a biomedical interaction repository with data compiled through comprehensive curation efforts. This challenge is dauntin��� Operated by the SIB Swiss Institute of Bioinformatics, Expasy, the Swiss Bioinformatics Resource Portal, provides access to scientific databases and software tools in different areas of life sciences. Version: 20.0 Atlas updated: 2020-11-19 release history Proteome analysis based on 26941 antibodies targeting 17165 unique proteins Sequence alignments Align two or more protein sequences using the Clustal Omega program. ●I-TASSER DisProt: database of experimental evidences of disorder in proteins (Indiana University School of Medicine, Temple University, University of Padua); InterPro: classifies proteins into families and predicts the presence of domains and sites; MobiDB: database of intrinsic protein disorder annotation (University of Padua); neXtProt: a human protein-centric knowledge resource ●TM-align Protein function prediction and annotation in an integrated environment powered by web service. ●ThreaDomEx Active and Flexible Data Storage. ●ResQ Select the Gene database on the results page, if possible, and continue with step 3 in the "A Gene Name" section above. 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